抗癌剂73 T60420
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 124811-87-6 | ¥3,730.00 | 询底价 |
25 mg | 124811-87-6 | ¥1,660.00 | 询底价 |
500 mg | 124811-87-6 | ¥7,880.00 | 询底价 |
50 mg | 124811-87-6 | ¥2,490.00 | 询底价 |
10 mg | 124811-87-6 | ¥828.00 | 询底价 |
1 mL | 124811-87-6 | ¥547.00 | 询底价 |
5 mg | 124811-87-6 | ¥495.00 | 询底价 |
1 mg | 124811-87-6 | ¥218.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Anticancer agent 73
描述: Anticancer agent 73 是一种抗癌剂,它能有效地靶向反式激活反应(TAR)RNA 结合蛋白2(TRBP),并破坏TRBP-Dicer 的相互作用。Anticancer agent 73 通过调节 HCC 细胞中 miRNA 组和蛋白质组的表达谱,在体外和体内抑制 HCC 的生长和转移。
体外活性: Anticancer agent 73 (compound CIB-3b) (10 μM; 6 h) induces an elevation in E-cadherin expression and reduces the protein levels of fibronectin, N-cadherin, and vimentin in SK-HEP-1 cells. Furthermore, it suppresses the proliferation and migration of SK-HEP-1, HCCLM3, and MHCC97L cells by impeding miRNA biogenesis.[1]
体内活性: Anticancer agent 73 (compound CIB-3b) (10, 25, and 50 mg/kg; i.v.; every 2 days for 4 weeks; SCID mice) diminishes the proliferation and migration of both SK-HEP-1 cells and SK-HEP-1 cells implanted in SCID mice.[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 90.0 mg/mL (344.5 mM)
相关产品: Nelarabine | Psoralen | SRE-II | Rimantadine hydrochloride | SL327 | WRN inhibitor 2 | T4 RNA ligase | RNA polymerase II-IN-1 | BRD32048 | NKP-1339
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Bioactive Compound Library
抗癌剂73 T60420信息由TargetMol中国为您提供,如您想了解更多关于抗癌剂73 T60420报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途