氨苄西林钠 T6386
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 g | 69-52-3 | ¥395.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Ampicillin sodium
描述: Ampicillin sodium (Domicillin) 是Ampicillin 的钠盐形式,是Ampicillin 的广谱半合成衍生物。它通过与青霉素结合蛋白结合来抑制细菌细胞壁的合成,从而抑制肽聚糖的合成,肽聚糖是细菌细胞壁的关键成分。
体外活性: Belonging to the penicillin group of beta-lactam antibiotics, ampicillin is able to penetrate Gram-positive and some Gram-negative bacteria. Ampicillin acts as a competitive inhibitor of the enzyme transpeptidase, which is needed by bacteria to make their cell walls. Ampicillin inhibits the third and final stage of bacterial cell wall synthesis in binary fission, which ultimately leads to cell lysis.
体内活性: Ampicillin is extremely effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[3]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[4]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[5].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : 68 mg/mL (183.1 mM)
Ethanol : 69 mg/mL (185.8 mM)
DMSO : 45 mg/mL (121.17 mM)
关键字: Antibiotic | inhibit | Inhibitor | Bacterial | D-a-Aminobenzylpenicillin sodium | Ampicillin | Ampicillin sodium | D-α-Aminobenzylpenicillin sodium | D-alpha-Aminobenzylpenicillin sodium
相关产品: Ethoxzolamide | Erianin | JFD01307SC | 2,2':5',2''-Terthiophene | 4-Hydroxycoumarin | Meldrum's acid | Fumitremorgin C | Fosfomycin calcium | 1-Deoxynojirimycin hydrochloride | F7H
相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Approved Drug Library | Drug-induced Liver Injury (DILI) Compound Library | Inhibitor Library | Pediatric Drug Library | Anti-Bacterial Compound Library | NO PAINS Compound Library | Covalent Inhibitor Library | Anti-Infection Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途