化合物CVT-12012 T6412
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 1018675-35-8 | ¥913.00 | 询底价 |
25 mg | 1018675-35-8 | ¥2,570.00 | 询底价 |
5 mg | 1018675-35-8 | ¥828.00 | 询底价 |
1 mg | 1018675-35-8 | ¥328.00 | 询底价 |
100 mg | 1018675-35-8 | ¥5,680.00 | 询底价 |
2 mg | 1018675-35-8 | ¥483.00 | 询底价 |
10 mg | 1018675-35-8 | ¥1,230.00 | 询底价 |
50 mg | 1018675-35-8 | ¥3,990.00 | 询底价 |
Product Introduction
Bioactivity
英文名: CVT-12012
描述: CVT-12012 是口服具有活性的硬脂酰-CoA 去饱和酶抑制剂,能够抑制大鼠微粒体和人 HEPG2 的活性,它们的IC50值分别为 38 nM,6.1 nM。
体内活性: CVT-12012 is highly potent in a human cell-based (HEPG2) SCD assay (IC(50)=6nM). This compound has 78% oral bioavailability in rats and is preferentially distributed into liver (76 times vs plasma) with relatively low brain penetration[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 125 mg/mL (287.75 mM)
关键字: Stearoyl-CoA Desaturase (SCD) | CVT 12012 | inhibit | Inhibitor | CVT-12012 | CVT12012
相关产品: MK-8245 | SCD1 inhibitor-4 | GSK1940029 | SSI-4 | XEN723 | Elemicin | A939572 | MF-438 | PluriSIn 1 | CAY10566
相关库: Anti-COVID-19 Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Inhibitor Library | Anti-Obesity Compound Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Orally Active Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途