硫酸头孢噻利 T6438
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 122841-12-7 | ¥825.00 | 询底价 |
1 mL | 122841-12-7 | ¥747.00 | 询底价 |
50 mg | 122841-12-7 | ¥2,360.00 | 询底价 |
5 mg | 122841-12-7 | ¥537.00 | 询底价 |
100 mg | 122841-12-7 | ¥3,996.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Cefoselis Sulfate
描述: Cefoselis Sulfate (FK 037 Sulfate) 是一种头孢菌素 β-内酰胺抗生素。它对多种革兰氏阳性和革兰氏阴性生物均表现出良好的活性。它可以透过血脑屏障。
体外活性: Cefoselis inhibits GABA-induced currents in a concentration-dependent manner with IC50 of 185 mM. [1] Cefoselis possesses a superior antistaphylococcal activity on MSSA isolates to both other compounds being however equal active to Cefepime and Cefpirome on multiresistant enterobacteriaceae. [2] Cefoselis is dose-dependently appeared in brain extracellular fluid in proportion to its blood level. [3] Cefoselis, a new parenteral cephalosporin, is active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. [4]
体内活性: Cefoselis elicits a massive elevation of extracellular glutamate concentration in normal rats. [3] Cefoselis (50 mg/animal)-induced convulsions are prevented by pretreatment with 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801), diazepam and phenobarbital (ED(50) values (mg/kg) of 0.78, 1.59 and 33.0, respectively), but not by carbamazepine or phenytoin. [5]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 27.5 mg/mL (44.31 mM)
关键字: Cefoselis | cephalosporin | Gram-negative | Gram-positive | Bacterial | FK 037 | barrier | FK037 | FK037 Sulfate | Inhibitor | Antibiotic | Cefoselis Sulfate | β-lactam | organisms | blood-brain | FK-037 Sulfate | inhibit
相关产品: Quadranoside III | Fosfomycin Tromethamine | Nonanoic acid | Clovamide | AU1235 | L-161240 | Pipemidic acid | G-418 disulfate | Povidone iodine | Morinidazole
相关库: Drug Repurposing Compound Library | Approved Drug Library | FDA-Approved & Pharmacopeia Drug Library | Beta-Lactam Compound Library | Bioactive Compounds Library Max | CNS-Penetrant Compound Library | Anti-Bacterial Compound Library | Covalent Inhibitor Library | Bioactive Compound Library | Anti-Infection Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途