钆双胺 T6508
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 122795-43-1 | ¥455.00 | 询底价 |
25 mg | 122795-43-1 | ¥316.00 | 询底价 |
100 mg | 122795-43-1 | ¥722.00 | 询底价 |
1 mL | 122795-43-1 | ¥728.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Gadodiamide Hydrate
描述: Gadodiamide Hydrate (Omniscan) 是一种造影剂,用于MR 中血管成像。它是非离子 Gd3+ 螯合物,经常静脉注射。 进入磁共振成像以增强对比度。
体内活性: Gadodiamide results in half-life of 18, 38, and 75 minutes in rats, rabbits, and monkeys, respectively. Gadodiamide is shown to be excreted rapidly, primarily through the kidneys. [1] Gadodiamide, when administered i.v. as gadodiamide injection at a dosage of 0.3 mmol/kg, is stable in vivo and that the very major part of the dose (> 99%) is excreted in urine as an unchanged complex. [2] Gadodiamide produces focal and generalized myoclonus over several hours. Gadodiamide itself produces lesions in the central cerebellar regions resembling in character and severity those produced by the gadodiamide formulation, but not others. [3] Gadodiamide travels quickly throughout the ventricular system from the lateral ventricular site of injection to the fourth ventricle and foramina of Luschka and Magendie within 2 min. [4] Gadodiamide results in transient but statistically significant decreases in aortic pressure, left ventricular pressure, indices of left ventricular contractility and relaxation, and systemic and pulmonary vascular resistance, and increases in aortic blood flow in anesthetized dogs. Gadodiamide injection produces less severe alterations in hemodynamics than gadopentetate dimeglumine. [5]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 16 mg/mL (27.04 mM)
关键字: inhibit | Gadodiamide | Gadodiamide Hydrate | Inhibitor
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途