黄素腺嘌呤二核苷酸 T65172

Product Introduction
Bioactivity


英文名: Flavin adenine dinucleotide

描述: Flavin adenine dinucleotide (FAD) 是一种氧化还原辅因子，是蛋白质的辅基，参与机体多种代谢反应。

体外活性: Characterized by an additional polymer-type redox reaction, Poly(Flavin adenine dinucleotide, FAD) is a highly effective electrocatalyst for NADH oxidation. Operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) exhibits an electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes demonstrate dramatically improved stability and are the most advantageous NADH transducers for analytical chemistry[2].

体内活性: Administered intravenously at a dose of 2 mg/kg, Flavin adenine dinucleotide significantly cancels the chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). The effect of CPZ on canine heart mitochondria is nullified by Flavin adenine dinucleotide. Following the injection of Flavin adenine dinucleotide, the dogs experience a transient hypotension within 10 minutes, after which their blood pressures recover to the initial level. Additionally, Flavin adenine dinucleotide prevents mitochondrial dysfunction induced by chlorpromazine[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 100 mg/mL (127.30 mM)


关键字: Flavin adenine dinucleotide

相关产品: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride | D-Melibiose | Nicotinamide riboside chloride | 5-Hydroxymethyluracil | Malic acid | γ-L-Glutamyl-L-alanine | Glucosamine hydrochloride | 3-Methyl-2-buten-1-ol | (S)-(−)-Perillyl alcohol | Dehydroascorbic acid

相关库: Bioactive Compounds Library Max | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途