化合物HO3867 T6537
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 1172133-28-6 | ¥458.00 | 询底价 |
200 mg | 1172133-28-6 | ¥7,360.00 | 询底价 |
1 mL | 1172133-28-6 | ¥678.00 | 询底价 |
50 mg | 1172133-28-6 | ¥3,390.00 | 询底价 |
10 mg | 1172133-28-6 | ¥1,060.00 | 询底价 |
100 mg | 1172133-28-6 | ¥5,390.00 | 询底价 |
25 mg | 1172133-28-6 | ¥2,120.00 | 询底价 |
5 mg | 1172133-28-6 | ¥663.00 | 询底价 |
1 mg | 1172133-28-6 | ¥328.00 | 询底价 |
Product Introduction
Bioactivity
英文名: HO-3867
描述: HO-3867是一种 STAT3的选择性有效抑制剂,有抗肿瘤活性。
细胞实验: Cell viability is determined by a colorimetric assay using MTT. In the mitochondria of living cells, yellow MTT undergoes a reductive conversion to formazan, producing a purple color. Cells, grown to ~80% confluence in 75-mm flasks, are trypsinized, counted, seeded in 96-well plates with an average population of 7,000 cells/well, incubated overnight, and then treated with HO-3867 for 24 h. All experiments are done using 8 replicates and repeated at least three times. (Only for Reference)
激酶实验: Scintillation Proximity Assay, 125I-FGF-2 Binding: SPA protein A beads are supplied as a suspension in PBS at 20 mg/mL, then diluted with binding buffer (KCl, 400 mg/L; MgSO4 200 mg/L; NaCl 6.4 g/L; NaHCO3 3.7 g/L; NaH2PO4 0.141 mg/mL; bis Tris Propane 11.292 g/L; Glucose 4.5 g/L; Gelatin 0.1 %; pH 7.0) at 10 mg/mL. 125I-FGF-2 radioligand and FGFR-1IIIc? - Fc Chimera are diluted into binding buffer. Binding was performed on 96-well plates coated with 0.1 % gelatin. Total assay volume is 0.1 mL. Binding of 125I-FGF-2 is determined by incubation of SPA beads coated with protein A (0.5 mg/assay) with FGFR-1IIIc? - Fc chimera soluble receptor (5 ng/assay), FGF-2 (20 ng/assay) is used for non-specific binding determinations.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 6 mg/mL (12.91 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 11 mg/mL (23.7 mM)
关键字: inhibit | Inhibitor | Apoptosis | STAT | HO-3867 | HO 3867
相关产品: Abacavir | ZNL 02-096 | AKT inhibitor VIII | Corilagin | BO-264 | Lacidipine | PHYTOSPHINGOSINE | AEG 3482 | Dihydrokaempferol | Triptolide
相关库: JAK-STAT Compound Library | Anti-Aging Compound Library | Transcription Factor-Targeted Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Cancer Compound Library | Ferroptosis Compound Library | Inhibitor Library | Highly Selective Inhibitor Library | Anti-Cancer Active Compound Library | Stem Cell Differentiation Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途