水飞蓟素 T6670
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 65666-07-1 | ¥248.00 | 询底价 |
500 mg | 65666-07-1 | ¥629.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Silymarin
描述: Silymarin (Silybin B) 是一种多酚类黄酮,是从水飞蓟或水飞蓟的种子中提取的一种 SARS-CoV-2 主蛋白酶抑制剂。它可降低肿瘤细胞的增殖,血管生成以及胰岛素抵抗,用于预防和治疗肝脏疾病,有潜力研究 COVID-19 。
体外活性: Mechanism of Silymarin involves different biochemical reactions, such as stimulation of the rate of ribosomal RNA synthesis by stimulating the transcription of polymerase I and ribosomal RNA genes, blockage of alpha-glycoside loops toxin intake, and protection of cell membranes from free radical-induced damage. Silymarin also displays a substantial protective effect against UVB-induced canceration at different stages, possibly through its strong antioxidant properties.
体内活性: Silymarin 的静脉注射LD50分别对于小鼠、大鼠、兔子为391.4 mg/kg、70.1 mg/kg、142.3 mg/kg。
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 45 mg/mL (93.28 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
Ethanol : 1 mg/mL (2.07 mM)
关键字: thistle | angiogenesis | Inhibitor | hepatocellular | resistance | SARS coronavirus | chemopreventive | inhibit | SARS-CoV | HCC | Milk | insulin | proliferation | carcinoma | Silymarin
相关产品: RdRP-IN-7 | Mefloquine hydrochloride | Narsoplimab | EIDD-1931 | GRL-0496 | Saquinavir | Glecaprevir | SARS-CoV-2-IN-43 | GS-441524 | SARS-CoV-2-IN-49
相关库: Drug Repurposing Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Chinese Pharmacopoeia Natural Product Library | Inhibitor Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library | Traditional Chinese Medicine Monomer Library | Anti-Cancer Active Compound Library | RO5 Drug-like Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途