替卡西林单钠盐单水合物 T6706
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 29457-07-6 | ¥160.00 | 询底价 |
25 mg | 29457-07-6 | ¥432.00 | 询底价 |
10 mg | 29457-07-6 | ¥273.00 | 询底价 |
50 mg | 29457-07-6 | 面议 | 询底价 |
Product Introduction
Bioactivity
英文名: Ticarcillin sodium
描述: Ticarcillin sodium (Aerugipen hydrate) 主要用于抗革兰氏阴性菌, 也能用于研究嗜麦芽感染。
体外活性: MICs of Ticarcillin (64 mg/mL) for 90% of all beta-lactamase-positive strains are reduced to 2 mg/mL, with the addition of clavulanate. MICs of Ticarcillin for 90% of all beta-lactamase-negative strains are 4 mg/mL. 93.4% of the beta-lactamase-producing strains are susceptible to Ticarcillin at less than or equal to 64 mg/mL. [1] Ticarcillin/potassium clavulanate is light stable and resistant to inactivation by β-lactamase. Ticarcillin/potassium clavulanate is more economical than carbenicillin and cefotaxime to eliminate Agrobacterium tumefaciens in plant transformation. [2]
体内活性: The mean elimination half-life of Ticarcillin (120 mg/kg) in serum is 70.8 minutes in the control subjects and 53.1 minutes in the patients with cystic fibrosis. The total body clearance of Ticarcillin is significantly higher in cystic fibrosis patients (65.6 mL/min/m2 versus 46.2 mL/min/m2 in control subjects). The nonrenal clearance of ticarcillin is also significantly higher in patients with cystic fibrosis (24.8 mL/min/m2 versus 13.3 mL/min/m2 for the control group). [3] Ticarcillin/clavulanate (3.1 g, given iv every 4-6 hours) results in clinical success rate of 80.3% and clinical failure rate of 19.7% in the treatment of complicated skin and skin-structure infections. The overall rate of eradication is 83.7% in the Ticarcillin/clavulanate treatment group in the microbiologically evaluable population. [4] Ticarcillin/clavulanate results in cure rates of 79% at the time of final assessment for the treatment of intra-abdominal infections in pediatric and adult patients. [5]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : < 1 mg/mL (insoluble or slightly soluble)
DMSO : 80 mg/mL (185.9 mM)
H2O : 79 mg/mL (183.5 mM)
关键字: Ticarpen Hydrate | Bacterial | Gram-negative | Inhibitor | inhibit | AB-2288 | Antibiotic | Ticarcillin | BRL-2288 | Ticarcillin sodium | AB2288 | Aerugipen Hydrate | BRL2288
相关产品: Afabicin | Sulfadiazine | BTZ043 Racemate | Fusidic acid | Quorum Sensing-IN-3 | Furagin | Etoposide | Proflavine | Patchouli alcohol | Povidone iodine
相关库: Approved Drug Library | Antibiotics Library | Beta-Lactam Compound Library | Anti-Bacterial Compound Library | NO PAINS Compound Library | Anti-Infection Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途