巴嗪普令 T67789

Product Introduction
Bioactivity


英文名: Bazinaprine

描述: Bazinaprine 是一种选择性的、可逆的单胺氧化酶抑制剂(MAOI)，是治疗抑郁症的候选化合物。Bazinaprine 对A 型单胺氧化酶显示出较强的抑制作用，对b 型单胺氧化酶只显示出较弱的抑制作用。Bazinaprine 在体内可逆，但在体外不可逆。

体外活性: Bazinaprine(SR 95191) inhibits MAO-A in a time-dependent manner in vitro and appears to be irreversible.[1] The inhibition of brain MAO-A, but not MAO-B, by SR 95191 was time dependent, with a 19-fold decrease in the IC50 values being observed over a 30-min incubation period (140 to 7.5 μM).[2]

体内活性: Bazinaprine (1–100 mg/kg, p.o.) antagonized, in a dose-dependent fashion, the irreversible inhibition of brain and liver MAO-A induced by phenelzine.[2]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 22.5 mg/mL (72.73 mM)


关键字: SR 95191 | Bazinaprine

相关产品: Cassiaside B2 | Tetrahydroharmine | Lazabemide hydrochloride | 4'-Demethyleucomin | CX-157 | 2614W94 | Paeonol | Fabomotizole hydrochloride | RN-1 dihydrochloride | Dihydroevocarpine

相关库: Anti-Neurodegenerative Disease Compound Library | Mitochondria-Targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Inhibitor Library | Bioactive Compound Library

巴嗪普令 T67789信息由TargetMol中国为您提供，如您想了解更多关于巴嗪普令 T67789报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途