化合物KM-023 T67804

Product Introduction
Bioactivity


英文名: KM-023

描述: KM-023是一种新的第二代非核苷类逆转录酶抑制剂，可用于研究人类免疫缺陷病毒（HIV）1型感染。

体内活性: KM-023 demonstrated dose- and time-dependent nonlinear pharmacokinetic characteristics after single or multiple doses over a dose range (75-600 mg) in healthy subjects. KM-023 showed a 0.6-fold accumulation after multiple doses in the 600 mg dose group. The mean half-life values ranged between 20.7 and 31.2 hours. KM-023 was generally well tolerated without serious adverse events. KM-023 showed favorable tolerability in this study.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 11 mg/mL (33.81 mM)


相关产品: Licoarylcoumarin | Nelfinavir | Tenofovir alafenamide fumarate | Helichrysetin | Zingibroside R1 | Ganodermanondiol | Flavopiridol | Cyclotriazadisulfonamide hydrochloride | Dolutegravir | Ebselen

相关库: Drug Repurposing Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Viral Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途