小檗碱熊去氧胆酸盐 T67974

Product Introduction
Bioactivity


英文名: Berberine ursodeoxycholate

描述: Berberine ursodeoxycholate (HTD1801) 是一种口服有效的降血脂剂 ，是 Berberine 和 Ursodeoxycholic acid 的一种离子盐。Berberine ursodeoxycholate 具有广泛的代谢活性，可显著降低肝脏脂肪含量。Berberine ursodeoxycholate 可用于研究高脂血症、非酒精性脂肪性肝炎 (NASH) 和糖尿病。

体内活性: Berberine ursodeoxycholate (BUDCA) tested in this phase 2 study (1000 mg twice a day) results in a significant reduction in liver fat content after 18 weeks of treatment. This improvement in liver fat content is associated with improvement in glycemic control, the apparent improvement in hepatic inflammation and injury with reductions in serum levels of liver associated enzymes, significant weight loss, and modest reductions in serum lipid levels.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 6.9 mg/mL (9.5 mM)


关键字: Berberine ursodeoxycholate | HTD-1801 | HTD 1801

相关库: Bioactive Compounds Library Max | Bioactive Compound Library

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