非唑拉明 T68070
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 mg | 80410-36-2 | ¥17,800.00 | 询底价 |
50 mg | 80410-36-2 | ¥6,490.00 | 询底价 |
25 mg | 80410-36-2 | ¥4,570.00 | 询底价 |
1 mg | 80410-36-2 | ¥780.00 | 询底价 |
10 mg | 80410-36-2 | ¥2,730.00 | 询底价 |
100 mg | 80410-36-2 | ¥8,890.00 | 询底价 |
5 mg | 80410-36-2 | ¥1,850.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Fezolamine
描述: Fezolamine 是一种新型可口服的非三环类化合物,具有抗抑郁活性。它在体外阻断[3H]去甲肾上腺素的突触体摄取方面的选择性是摄取[4H]3-羟色胺或[3H]多巴胺的3至2倍。在使用单胺耗尽动物的经典行为测试中,它阻止了利血平和四苯的抑制作用。
体内活性: Fezolamine (100-450 mg/day; oral; 6 weeks; 42 patients) significant improvement relative to the patient's prestudy state was observed after 2 weeks in both patient and physician-rating scales. Fifty-five percent of patients improved their Hamilton Psychiatric Rating Scale for Depression (HAM-D) scores by more than 50%. The median dose associated with a clinically significant response was 245 mg/day. Five of the 6 patients who dropped out did so because of gastrointestinal adverse effects. The most common adverse effects were nausea (36%), headache (29%), constipation (26%), and dry mouth (24%).[1]
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (180.08 mM)
相关产品: Amitriptyline hydrochloride | Phenelzine | Centanafadine hydrochloride | Tedatioxetine hydrobromide | Liafensine | Clomipramine hydrochloride | Dextromilnacipran | Ansofaxine hydrochloride | Nisoxetine hydrochloride | Amitriptyline
相关库: Anti-Neurodegenerative Disease Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途