化合物Scio-323 T68139

Product Introduction
Bioactivity


英文名: Scio-323

描述: Scio-323是一种可口服的 p38丝裂原活化蛋白（MAPK）激酶抑制剂。

体内活性: Oral treatment with the SCIO-323 included delivery for 3 weeks and stopping for 3 weeks, delivery for 3 weeks after an initial 3-week delay, and delivery for 6 weeks continuously. Administration of the SCIO-323 continuously for 6 weeks with/without the presence of particles, or for the initial 3 of 6 weeks had minor effects on bone ingrowth. After establishing a particle-induced chronic inflammatory reaction for 3 weeks, administration of SCIO-323 for a subsequent 3 weeks suppressed net bone formation. The activity of osteoclast-like cells remained low among all treatments when compared with the first control.[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 27.5 mg/mL (57.35 mM)


相关产品: BI-3406 | Sauchinone | Broussonin E | AL 8697 | Talmapimod | Obacunone | Neoechinulin A | Akt/NF-κB/MAPK-IN-1 | N-​Feruloyloctopamine | SU9516

相关库: Bioactive Compounds Library Max | Inhibitor Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途