化合物 Apilimod HCl T68485
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 870087-37-9 | ¥13,800.00 | 询底价 |
25 mg | 870087-37-9 | ¥10,600.00 | 询底价 |
100 mg | 870087-37-9 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Apilimod HCl
描述: Apilimod dimesylate is a potent and selective PIKfyve inhibitor. It exhibits no significant activity at other lipid kinases and protein kinases, including PIP4K, PIP5K, mTOR, PI3K and PI4K. Apilimod dimesylate inhibits cellular entry by SARS-CoV-2, MERS-CoV and MHV S pseudovirions. It reduces the number of SARS-CoV-2-infected hiPSC-derived pneumocyte-like cells by 85% and inhibits SARS-CoV-2 replication in donor lung tissue. It also exhibits selective cytotoxicity in B-cell non-Hodgkin lymphoma compared with normal cells and inhibits production of IL-12 and IL-23. Apilimod dimesylate is also anti-inflammatory and water-soluble.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Apilimod hydrochloride | LAM002 | STA-5326 | STA5326 | STA 5326 | LAM 002 | LAM-002 | Apilimod HCl
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途