化合物 Brivudine monophosphate T68656
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 80860-82-8 | ¥13,900.00 | 询底价 |
50 mg | 80860-82-8 | ¥18,300.00 | 询底价 |
100 mg | 80860-82-8 | ¥23,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Brivudine monophosphate
描述: Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator of transcription 3), which may result in the downregulation of vascular endothelial growth factor (VEGF). BVDU has also been found to inhibit the upregulation of chemoresistance genes (Mdr1 and DHFR) during chemotherapy.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Brivudine Monophosphate | Brivudine | Bvdu5'-monophosphate | Bvdu-5'-monophosphate | Bvdu 5'-monophosphate
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途