化合物 Iso-Fludelone T68860
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 691868-19-6 | ¥10,600.00 | 询底价 |
50 mg | 691868-19-6 | ¥13,800.00 | 询底价 |
100 mg | 691868-19-6 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Iso-Fludelone
描述: Iso-Fludelone is the third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites. Iso-fludelone binds to tubulin and induces microtubule polymerization and stabilizes microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. Compared to other generations of epothilones, iso-fludelone exhibits increased stability, water solubility, potency, duration of action, tumor penetration as well as reduced toxicity. In addition, this agent is a not a substrate of the P-glycoprotein (P-gp), a multidrug resistance pump often overexpressed in cancer cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Iso-Fludelone | KOS-1803 | KOS1803
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途