化合物 Phenytoin-d10 T68918

Product Introduction
Bioactivity


英文名: Phenytoin-d10

描述: Phenytoin-d10 is intended for use as an internal standard for the quantification of phenytoin by GC- or LC-MS. Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin. Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal slices. It protects against seizures induced by maximal electroshock (MES) in mice. Formulations containing phenytoin have been used in the treatment of tonic-clonic seizures and status epilepticus.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: Phenytoin-d10 | 5,5-Diphenylhydantoin-d10 | 5,5-Diphenylhydantoin d10 | Phenytoin d10

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