化合物 Difelikefalin HCl T69537
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 2711717-77-8 | ¥13,900.00 | 询底价 |
50 mg | 2711717-77-8 | ¥18,300.00 | 询底价 |
100 mg | 2711717-77-8 | ¥23,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Difelikefalin HCl
描述: Difelikefalin HCl is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin HCl is selective for KOR over the μ-opioid receptor (MOR; EC50 = >1 µM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.05 mg/kg, respectively).
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: FE 202845 | FE202845 | CR 845 | CR845 | FE-202845 | Difelikefalin HCl | Difelikefalin hydrochloride | CR-845
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途