Sarizotan 盐酸盐 T70044
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 195068-07-6 | ¥13,800.00 | 询底价 |
5 mg | 195068-07-6 | ¥4,920.00 | 询底价 |
10 mg | 195068-07-6 | ¥7,130.00 | 询底价 |
1 mg | 195068-07-6 | ¥1,980.00 | 询底价 |
25 mg | 195068-07-6 | ¥10,600.00 | 询底价 |
2 mg | 195068-07-6 | ¥2,970.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Sarizotan HCl
描述: Sarizotan, also known as EMD-128130, is a Dopamine D2 receptor partial agonist and Serotonin 1A receptor agonist. Sarizotan exhibits affinity at serotonin and dopamine receptors. Sarizotan effectively suppresses levodopa-induced dyskinesia in primate and rodent models of Parkinson's disease, and tardive dyskinesia in a rodent model. Sarizotan is a full agonist at D3 and D4.4 receptors (EC50=5.6 and 5.4 nM, respectively) but a partial agonist at D2S, D2L and D4.2 receptors (EC50=29, 23 and 4.5 nM, respectively). Sarizotan is an antagonist at D2S and D2L receptors (IC50=52 and 121 nM, respectively). Sarizotan is a full agonist at D2L, D3, D4.2 and D4.4 receptors (EC50=0.51, 0.47, 0.48 and 0.23 nM, respectively) but a partial agonist at D2S receptors (EC50=0.6 nM).
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: HUN 47990 | HUN-47990 | Sarizotan HCl
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途