化合物 ELND006 T70951

Product Introduction
Bioactivity


英文名: ELND006

描述: ELND006 is a novel gamma secretase inhibitor previously under investigation for the oral treatment of Alzheimer's disease. ELND006 shows poor solubility and has moderate to high permeability. The in vivo performance of the ELND006 nanosuspension was tested in fed and fasted beagle dogs and compared with a gelatin capsule containing reference API. The results show that nanosizing ELND006 profoundly improved the oral bioavailability and virtually eliminated variation resulting from food intake.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: AZ-5576 | ELND-006 | ELND006 | AZ 5576 | AZ5576 | ELND 006

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途