依米地肽 T7107

Product Introduction
Bioactivity


英文名: δ-Sleep Inducing Peptide

描述: δ-Sleep Inducing Peptide (DSIP) 是一种具有抗氧化和抗焦虑活性的神经肽。

动物实验: The rats divided in four groups received (i.p.): saline; metaphit; metaphit+DSIP; and metaphit+DSIP-12, respectively. Metaphit-treated animals displaying seizure in eight previous tests received DSIP or DSIP-12 and afterwards audiogenic stimuli were applied at hourly intervals for the next 30 h. The animals were exposed to sound stimulation 60 min after metaphit administration and further on at hourly intervals. Incidence and severity of seizures were behaviorally analyzed. Selected EEGs and power spectra were recorded and analyzed[1].

体内活性: Delta-Sleep Inducing Peptide(DSIP) and DSIP-12 significantly (*P<0.05 and **P<0.01) increased in delta and theta frequency bands and decreased the incidence, mean seizure grade and duration of metaphit convulsions. Suggest that DSIP and DSIP-12 may be considered as potential antiepileptics in the animal model[1].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 10 mM


关键字: Inhibitor | inhibit | δSleep Inducing Peptide | δ Sleep Inducing Peptide | Δ-Sleep Inducing Peptide | δ-Sleep Inducing Peptide

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