化合物 CHS-828 nicotinate T71361
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 1160589-73-0 | ¥10,600.00 | 询底价 |
100 mg | 1160589-73-0 | ¥17,500.00 | 询底价 |
50 mg | 1160589-73-0 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: CHS-828 nicotinate
描述: CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients. CHS 828 showed a synergistic effect with melphalan in 67%, doxorubicin in 47%, etoposide in 38% and Ara-C in 14% of AML samples.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: ACT 281959 | ACT281959. | CHS-828 nicotinate
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途