化合物 Oxaliplatin-d10 T71401
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 1132819-16-9 | ¥13,800.00 | 询底价 |
100 mg | 1132819-16-9 | ¥17,500.00 | 询底价 |
25 mg | 1132819-16-9 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Oxaliplatin-d10
描述: Oxaliplatin-d10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts, inhibits DNA and RNA synthesis, and induces apoptosis in cancer cells. Oxaliplatin is cytotoxic to cisplatin-sensitive A2780(1A9) and KB-3-1 cells and cisplatin-resistant A2780-E(80) and KB-CP20 cells (IC50s = 0.12, 0.39, 4.7, and 2.7 µM, respectively). It reduces tumor growth in an HCCLM3 mouse xenograft model when administered at doses of 5 or 10 mg/kg once per week. Formulations containing oxaliplatin have been used in the treatment of advanced colorectal cancer and as adjuvants in stage III colon cancer.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: PZ 09 | Oxaliplatin-d10 | PZ09 | PZ-09 | PKC9 | PKC 9
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途