化合物 AFN-1252 tosylate hydrate T71539
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 1047981-30-5 | ¥13,800.00 | 询底价 |
25 mg | 1047981-30-5 | ¥10,600.00 | 询底价 |
100 mg | 1047981-30-5 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AFN-1252 tosylate hydrate
描述: AFN-1252, also known as AFN-12520000; API-1252; Debio-1452, is FASII Inhibitor which is potentially for the treatment of acute bacterial skin. AFN-1252 exhibits typical MIC(90) values of ≤0·015 μg/ml against diverse clinical isolates of S. aureus, oral absorption, long elimination half-live and efficacy in animal models. AFN-1252 efficiently blocked daptomycin-induced phospholipid decoy production, even in the case of isolates resistant to AFN-1252, which prevented the inactivation of daptomycin and resulted in sustained bacterial killing. In turn, daptomycin prevented the fatty acid-dependent emergence of AFN-1252-resistant isolates in vitr
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: ASP 9133 | ASP9133 | AFN-1252 tosylate Hydrate
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途