化合物 SC-10914 T71757
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 76985-08-5 | ¥10,600.00 | 询底价 |
50 mg | 76985-08-5 | ¥13,800.00 | 询底价 |
100 mg | 76985-08-5 | ¥17,500.00 | 询底价 |
Product Introduction
Bioactivity
英文名: SC-10914
描述: SC10914 is a highly potent PARP inhibitor (PARP1 IC50 = 7.87 nM) with potent anti-proliferative activity against human BRCA deficient tumor cells (MDA-MB-436, BRCA1 deficient, IC50 = 4.03 nM, Capan-1 BRCA2 deficient, IC50 = 11.66 nM) and PTEN deficient tumor cells (HGC-27,PTEN deficient, IC50 = 0.35 μM). SC10914 showed potent anti-tumor activity in BRCA1/2 mutant tumor models and better pharmacokinetics profile has the potential to be selected as the clinical candidate for the treatment of treatment of BRCA1/2 deficient cancers.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: SC10914 | SC 10914 | SC-10914
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途