二苯基氯化碘盐 T7191
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 4673-26-1 | ¥1,890.00 | 询底价 |
25 mg | 4673-26-1 | ¥1,160.00 | 询底价 |
100 mg | 4673-26-1 | ¥3,230.00 | 询底价 |
5 mg | 4673-26-1 | ¥398.00 | 询底价 |
1 mg | 4673-26-1 | ¥179.00 | 询底价 |
10 mg | 4673-26-1 | ¥638.00 | 询底价 |
1 mL | 4673-26-1 | ¥452.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Diphenyleneiodonium chloride
描述: Diphenyleneiodonium chloride (DPI) 是 NADPH 氧化酶抑制剂,也是 TRPA1激活剂,EC50为 1 - 3 μM 。它选择性抑制胞内活性氧。
细胞实验: Whole-cell growth inhibition assays were used to screen and identify novel inhibitors. The hit compounds(Diphenyleneiodonium chloride) were tested for cytotoxicity against Vero cells to determine the selectivity index, and time-kill kinetics were determined against Mycobacterium fortuitum. The compound's ability to synergize with amikacin, ceftriaxone, ceftazidime and meropenem was determined using fractional inhibitory concentration indexes followed by its ability to decimate mycobacterial infections ex vivo[1].
体外活性: Diphenyleneiodonium chloride (DPIC), an NADPH/NADH oxidase inhibitor, as possessing potent antimicrobial activity against non-tuberculous mycobacteria.?DPIC exhibited concentration-dependent bactericidal activity against M. fortuitum and synergized with amikacin, ceftriaxone, ceftazidime and meropenem[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 6 mg/mL (19.07 mM)
关键字: NADPH Oxidase | Diphenyleneiodonium | inhibit | Reactive Oxygen Species | NOX | Diphenyleneiodonium Chloride | Diphenyleneiodonium chloride | TRP Channel | Transient receptor potential channels | Inhibitor
相关产品: Neotuberostemonine | Ermanin | Lupeol acetate | 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid | Eupatolide | Triptoquinone A | Bakkenolide B | 1400W dihydrochloride | Tetrahydrobiopterin | Cannabigerol
相关库: Antioxidant Compound Library | Anti-Neurodegenerative Disease Compound Library | Anti-Liver Cancer Compound Library | Anti-Parkinson's Disease Compound Library | Oxidation-Reduction Compound Library | NF-κB Signaling Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Highly Selective Inhibitor Library | Cuproptosis Compound Library
二苯基氯化碘盐 T7191信息由TargetMol中国为您提供,如您想了解更多关于二苯基氯化碘盐 T7191报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途