双醋酚丁 T7311
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 115-33-3 | ¥656.00 | 询底价 |
10 mg | 115-33-3 | ¥413.00 | 询底价 |
100 mg | 115-33-3 | ¥1,330.00 | 询底价 |
1 mL | 115-33-3 | ¥387.00 | 询底价 |
500 mg | 115-33-3 | ¥3,330.00 | 询底价 |
50 mg | 115-33-3 | ¥913.00 | 询底价 |
5 mg | 115-33-3 | ¥255.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Oxyphenisatin acetate
描述: Oxyphenisatin acetate 是oxyphenisatin 的前体药物,可抑制乳腺癌细胞系 MCF7、T47D、HS578T 和 MDA-MB-468 的生长。
细胞实验: Total RNA was isolated from MCF7 cells treated with 10 μmol/L OXY for 24 h and the microarray procedure performed as described previously using the GeneChip Human U133 plus 2.0 array . Pairwise analysis was performed on control versus treated arrays using a fivefold change cutoff, <0.01 adjusted P-value, GC-RMA normalization with Benjamini–Hochberg false discovery estimation[1].
体外活性: In the estrogen receptor (ER) positive MCF7 and T47D cells, OXY induced TNFα expression and TNFR1 degradation, indicating autocrine receptor-mediated apoptosis in these lines. Lastly, in an MCF7 xenograft model, OXY delivered intraperitoneally inhibited tumor growth, accompanied by phosphorylation of eIF2α and degradation of TNFR1. OXY induces a multifaceted cell starvation response, which ultimately induces programmed cell death[1].
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 150 mg/mL (373.68 mM)
关键字: Autophagy | Oxyphenisatin acetate | inhibit | Inhibitor | Oxyphenisatin Acetate | Oxyphenisatin
相关产品: Perifosine | CA-5f | Flavopiridol hydrochloride | Physalin H | Crustecdysone | Samotolisib | EACC | FERULIC ACID METHYL ESTER | Paeonol | BIX-01294 trihydrochloride
相关库: Anti-Aging Compound Library | Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Endoplasmic Reticulum Stress Compound Library | Anti-Cancer Active Compound Library | Autophagy Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途