反式-2-癸烯酸 T7332

Product Introduction
Bioactivity


英文名: (E)-2-Decenoic acid

描述: (E)-2-Decenoic acid (trans-2-Decenoic acid) 是一种存在于蜂王浆中的脂肪酸。

体外活性: Trans-2-decenoic acid does not inhibit AI-2-specific signaling, but rather the luciferase reaction used for its detection. A potential biological role of trans-2-decenoic acid was then discovered. It is able to suppress the transition from yeast to hyphal morphology in the opportunistic human pathogen Candida albicans at concentrations that do not affect growth. The expression of HWP1, a hyphal-specific signature gene of C. albicans, is abolished by trans-2-decenoic acid. trans-2-Decenoic acid is structurally similar to the diffusible signal factor (DSF) family of interkingdom-signaling molecules and is the first member of this family from a Gram-positive organism (Streptococcus DSF, SDSF). SDSF activity was also found in S. mitis, S. oralis, and S. sanguinis, but not in other oral bacteria. SDSF could be relevant in shaping multispecies Candida bacteria biofilms in the human body[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (587.37 mM)


关键字: inhibit | Inhibitor | (E)2Decenoic acid | 2-Decenoic acid | (E) 2 Decenoic acid

相关库: Bioactive Compounds Library Max | Food Additive Library | NO PAINS Compound Library | Bioactive Compound Library

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