羟基豪莫西地那非 T7346
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 139755-85-4 | ¥787.00 | 询底价 |
2 mg | 139755-85-4 | ¥477.00 | 询底价 |
10 mg | 139755-85-4 | ¥1,230.00 | 询底价 |
25 mg | 139755-85-4 | ¥2,190.00 | 询底价 |
1 mg | 139755-85-4 | ¥329.00 | 询底价 |
100 mg | 139755-85-4 | ¥4,560.00 | 询底价 |
50 mg | 139755-85-4 | ¥3,270.00 | 询底价 |
1 mL | 139755-85-4 | ¥868.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Lodenafil
描述: Lodenafil (Hydroxyhomosildenafil) 是一种有效的磷酸二酯酶 5 型(PDE5)抑制剂,可用于勃起功能障碍的研究。
动物实验: Thirty male Sprague-Dawley rats were randomly divided into three groups: control; monocrotaline (experimental model); and lodenafil (experimental model followed by lodenafil treatment, 5 mg/kg daily for 28 days) Mean pulmonary artery pressure (mPAP) was obtained by right heart catheterization[1].
体内活性: Investigated right ventricular hypertrophy (RVH) and IL-1 levels in lung fragments. The number of cases of RVH was significantly higher in the monocrotaline group than in the lodenafil and control groups, as were mPAP and IL-1 levels. Lodenafil can prevent monocrotaline-induced PH, RVH, and inflammation[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 250 mg/mL (495.44 mM)
关键字: inhibit | Lodenafil | Phosphodiesterase (PDE) | Inhibitor
相关产品: CP671305 | BI 1015550 | 5-Bromoimidazo[1,2-A]Pyrazine | PDE7-IN-2 | Mardepodect hydrochloride | ATX inhibitor 1 | BC 11-38 | ITI-214 | Olprinone | PF-04957325
相关库: Drug Repurposing Compound Library | Anti-Neurodegenerative Disease Compound Library | ReFRAME Related Library | Clinical Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Cardiovascular Disease Compound Library | Anti-Alzheimer's Disease Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途