2'-甲氧基肉桂醛 T7452

Product Introduction
Bioactivity


英文名: 2-methoxycinnamaldehyde

描述: 2-methoxycinnamaldehyde 是一种肉桂中的天然产物。它能通过使线粒体膜电位 (ΔΨm) 损失 、激活 caspase-3 和 caspase-9，来抑制细胞增殖和诱导细胞凋亡，具有抗肿瘤活性。它还能抑制血小板衍生生长因子诱导的 HASMC 迁移。

细胞实验: Cells were seeded in 96-well culture plates (1×10^4 cells/well). After incubated for 24 hours, the cells were treated with different concentrations of 2-MCA for 24 hours, 48 hours, and 72 hours. The cell viability was determined by Cell Proliferation Kit II (XTT) following the manufacturer's protocol. The absorbance was measured using Tecan infinite M200 spectrophotometer at 492 nm with a reference wavelength of 650 nm[1].

体外活性: 2-methoxycinnamaldehyde(2-MCA) inhibited cell proliferation in SK-Hep-1 cells in a dose- and time-dependent manner. The inhibitory concentration (IC50) value following 48 hours of incubation was 25.72 μM[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/mL (369.94 mM)


关键字: 2-methoxycinnamaldehyde | 2methoxycinnamaldehyde | 2 methoxycinnamaldehyde | 2-Methoxycinnamaldehyde | Apoptosis | inhibit | Inhibitor

相关产品: MRS 2578 | Tubeimoside I | JIB-04 | 9-ING-41 | Cucurbitacin IIb | 6-Azauridine | Monomethyl auristatin E | Capecitabine | Riviciclib hydrochloride | NSC 146109 hydrochloride

相关库: Anti-Tumor Natural Product Library | Tobacco Monomer Library | Covalent Natural Product Library | Food Additive Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Traditional Chinese Medicine Monomer Library | Traditional Mongolian Medicine Compound Library | Natural Product Library | Bioactive Compound Library

2'-甲氧基肉桂醛 T7452信息由TargetMol中国为您提供，如您想了解更多关于2'-甲氧基肉桂醛 T7452报价、型号、参数等信息，欢迎来电或留言咨询。

注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途