3-氯-5-羟基苯甲酸 T7482

Product Introduction
Bioactivity


英文名: 3-chloro-5-hydroxybenzoic Acid

描述: 3-Chloro-5-hydroxybenzoic acid 是一种口服具有活力的乳酸受体GPR81选择性激动剂，对人 GPR81 的EC50为 16 μM。肥胖小鼠模型中，它表现出良好的体内脂肪分解作用。

体内活性: 3-chloro-5-hydroxybenzoic Acid is similarly effective at GPR81 receptors from a variety of mammalian species and is bioavailable, stimulating lipolysis (increased serum free fatty acids) in mice fed high fat chow for 10 weeks[1]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 34mg/mL(197.03mM)


关键字: Inhibitor | GPR81 | 3 chloro 5 hydroxybenzoic Acid | 3chloro5hydroxybenzoic Acid | obesity | nonesterified free fatty acid | 3-chloro-5-hydroxybenzoic Acid | cholesterol | lactate receptor | inhibit

相关产品: Kuwanon H | RTI-13951-33 | CAY10595 | GW-1100 | Latanoprost acid | AF64394 | GPR40/FFAR1 modulator 1 | P2Y2R/GPR17 antagonist 1 | (2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid | Lodoxamide

相关库: Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Endocrinology-Hormone Compound Library | Orally Active Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途