GRGDSPK醋酸盐 T7566L1
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 144027-77-0 | ¥9,480.00 | 询底价 |
1 mL | 144027-77-0 | ¥4,300.00 | 询底价 |
1 mg | 144027-77-0 | ¥1,290.00 | 询底价 |
5 mg | 144027-77-0 | ¥2,990.00 | 询底价 |
100 mg | 144027-77-0 | ¥12,800.00 | 询底价 |
25 mg | 144027-77-0 | ¥6,910.00 | 询底价 |
500 mg | 144027-77-0 | ¥25,600.00 | 询底价 |
10 mg | 144027-77-0 | ¥4,390.00 | 询底价 |
Product Introduction
Bioactivity
英文名: GRGDSPK acetate
描述: GRGDSPK acetate 显示出对整合素-纤连蛋白结合的抑制活性,可用于研究整合素在骨形成和吸收中的作用。
体外活性: By measuring calcium content and 70 bonehnit area of tissue in parietal bones 18 days old isolated from pregnant Sprague-Dawley rats, we know that GRGDSPK (EMD 56574; RGD; 0.1-50 μM; for 4 days) inhibits mineralization in a dose-dependent manner.[1]Treatment with GRGDSPK (10 and 50 μM; 4-day treatment) results in significant alterations in bone morphology, characterized by disruptions in the organization of osteoblasts and the mineralized matrix.[1]In the presence of GRGDSPK peptide (RGD; 250 μM), added to the medium, the binding between integrins and fibronectin is effectively blocked, leading to a considerable increase in the average size of cell aggregates in wild-type cells.[2]Addition of GRGDSPK (250 μM) leads to a significant reduction in adhesion forces and work exerted by wild-type mesendodermal progenitors, indicating the involvement of integrins expressed in these progenitors and the specificity of the detachment parameters recorded for fibronectin.[2]GRGDSPK (RGD-containing, 1.5 mM, 1.0 mM, and 0.5 mM) and RGD-modified peptides, at concentrations of 1.5 mM, 1.0 mM, and 0.5 mM, impair the fertilization ability of bovine oocytes by sperm cells, resulting in a dose-dependent reduction in cleavage rates.[3]
存储条件: store at low temperature,keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 7.76 mg/mL (10 mM)
关键字: GRGDSPK Acetate
相关产品: 4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine | LY 2389575 hydrochloride | GSNKGAIIGLM(131602-53-4(free base)) | Pinostrobin | DC-Chol hydrochloride | Ginsenoside Re | Tolcapone | (Rac)-Z-Phe-Phe-FMK | Cedrin | TAE-1
相关库: Anti-Neurodegenerative Disease Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | Peptide Compound Library | Bioactive Compound Library
GRGDSPK醋酸盐 T7566L1信息由TargetMol中国为您提供,如您想了解更多关于GRGDSPK醋酸盐 T7566L1报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途