L-2,4-二氨基丁酸氢溴酸盐 T7595

Product Introduction
Bioactivity


英文名: L-DABA

描述: L-DABA (L-2,4-Diaminobutyric acid) 是GABA 转氨酶的弱抑制剂，IC50值大于500 μM，具有抗肿瘤活性。

体外活性: L-2,4-Diaminobutyric acid(DABA) was a non-linear, non-competitive inhibitor of GABA transaminase activity. The DABA-induced elevation of GABA levels paralleled the inhibition of GABA transaminase activity. DABA was a more effective inhibitor of GABA transaminase in vivo than in vitro, and this inhibition probably produced the elevation of GABA levels. The neurotoxicity of DABA appears to produce a use in GABA replacement therapy[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : Insoluble
H2O : Insoluble


关键字: Gamma-aminobutyric acid Receptor | Inhibitor | inhibit | LDABA | GABA Receptor | L DABA | Endogenous Metabolite | γ-Aminobutyric acid Receptor | L-DABA

相关产品: Lorediplon | Gabazine | Imepitoin | Bifenazate | L-Cycloserine | DL-Menthol | MmTx2 toxin | Cannabidivarin | Suriclone | COR659

相关库: RO5 Drug-like Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途