化合物ARS-1620 T7609

Product Introduction
Bioactivity


英文名: ARS-1620

描述: ARS-1620 是 K-RASG12C 的共价抑制剂，具有理想的药代动力学。

体内活性: ARS-1620 (200 mg/kg) induces tumor regression in a MIA-PaCa2, but not an H441, mouse xenograft model.?It also decreases tumor volume in patient-derived xenograft (PDX) mouse models expressing K-RASG12C, but not K-RASG12D or wild-type K-RAS.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 53 mg/mL (123.02 mM)


关键字: inhibit | Ras | Inhibitor | ARS 1620 | ARS1620 | ARS-1620

相关产品: EHT 1864 | (S)-AMG-510 | KRAS G12C inhibitor 32 | Salirasib | Antineoplaston A10 | Glecirasib | Garsorasib | 1588-A4 | Cysmethynil | KRAS inhibitor-9

相关库: Anti-Cancer Metabolism Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Inhibitor Library | GPCR Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途