EBV 裂解循环诱导剂-1 T77753

Product Introduction
Bioactivity


英文名: EBV lytic cycle inducer-1

描述: EBV lytic cycle inducer-1 是一种铁螯合类似物，可诱导EBV 裂解循环。

体外活性: Dp44mT (EBV lytic cycle inducer-1)(compound C7) induces the lytic cycle in a cell-line-dependent manner, with a higher inductive capacity on AGS-BX1 cells compared to AGX cells, in the concentration range of 0-80 μM for 48 hours[1].At 10 μM, Dp44mT(EBV lytic cycle inducer-1) induces the lytic cycle in a time-dependent manner over 0-72 hours[1].At concentrations of 1.25-2.5 μM for 24 hours, Dp44mT(EBV lytic cycle inducer-1) synergistically induces the Epstein-Barr virus (EBV) lytic cycle with the HDAC inhibitors Romidespin and SAHA[1].At 20 μM for 48 hours, Dp44mT(EBV lytic cycle inducer-1) reactivates the EBV lytic cycle by inducing the ERK-autophagy axis[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 1mg/ml


关键字: EBV lytic cycle inducer-1

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相关库: Bioactive Compounds Library Max | Bioactive Compound Library

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