化合物MLS000532223 T8473

Product Introduction
Bioactivity


英文名: MLS000532223

描述: MLS000532223 是一种具有高亲和力的 Rho 家族 GTPases 选择性抑制剂，其EC50=16~120 μM。它能阻止几种 GTPases 同 GTP 的结合。

体外活性: MLS000532223, a general inhibitor that prevents GTP binding to several GTPases in a dose-dependent manner and is active in biochemical and cell-based secondary assays.?Live-cell imaging and confocal microscopy studies revealed the inhibitor-induced actin reorganization and cell morphology changes, characteristic of Rho GTPases inhibition.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 45 mg/mL (179.11 mM)


关键字: GTPases | Inhibitor | MLS000532223 | Rab | cytoskeleton | MLS 000532223 | actin | Rho GTPases | Ras | MLS-000532223 | inhibit

相关产品: Azathioprine | SAR407899 | EHT 1864 | YH-306 | CCG-1423 | Rhosin hydrochloride | (E/Z)-ZINC09659342 | Digeranyl bisphosphonate | ITX3 | Rhosin

相关库: Membrane Protein-targeted Compound Library | Ferroptosis Compound Library | Anti-Ovarian Cancer Compound Library | Inhibitor Library | GPCR Compound Library | Kinase Inhibitor Library | Anti-Colorectal Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Covalent Inhibitor Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途