N-(4-氯苯甲酰)-L-色氨酸 T8578
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 39544-74-6 | ¥4,320.00 | 询底价 |
1 mL | 39544-74-6 | ¥2,910.00 | 询底价 |
2 mg | 39544-74-6 | ¥1,930.00 | 询底价 |
50 mg | 39544-74-6 | ¥9,330.00 | 询底价 |
5 mg | 39544-74-6 | ¥2,920.00 | 询底价 |
25 mg | 39544-74-6 | ¥6,890.00 | 询底价 |
100 mg | 39544-74-6 | ¥12,500.00 | 询底价 |
1 mg | 39544-74-6 | ¥1,290.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Benzotript
描述: Benzotript 是一种胃泌素受体拮抗剂,具有抗胃泌素作用。
体外活性: proglumide and benzotript, a new tryptophan derivative, to inhibit acid output from isolated gastric fundic parietal cells from rabbit.?As measured with the [14C]aminopyrine (AP) accumulation method as an index of acid secretion, the two drugs inhibited basal AP with IC-50 values of 1 X 10(-2) M for proglumide and 1 X 10(-3) M for benzotript.?In the case of secretagogue stimulation (1) benzotript slightly affected histamine-induced AP (15% inhibition at 5 X 10(-3) M), proglumide did not;?(2) both proglumide and benzotript inhibited in a non-competitive manner acetylcholine-induced AP;?(3) these isolated cells were sensitive to gastrin and the dose-response curve for the stimulant was biphasic (maximum for 1 X 10(-9) M), suggesting a desensitization mechanism.?Proglumide and benzotript competitively inhibited both [125I]gastrin binding to its receptor sites and gastrin-induced AP, suggesting they are members of a class of gastrin-receptor antagonists.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL (29.17 mM)
关键字: Benzotript
相关库: Bioactive Compounds Library Max | Human Metabolite Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途