化合物BC-1258 T8956
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 1507370-40-2 | ¥2,660.00 | 询底价 |
1 mg | 1507370-40-2 | ¥195.00 | 询底价 |
10 mg | 1507370-40-2 | ¥788.00 | 询底价 |
100 mg | 1507370-40-2 | ¥3,930.00 | 询底价 |
1 mL | 1507370-40-2 | ¥597.00 | 询底价 |
25 mg | 1507370-40-2 | ¥1,660.00 | 询底价 |
5 mg | 1507370-40-2 | ¥493.00 | 询底价 |
Product Introduction
Bioactivity
英文名: BC-1258
描述: BC-1258 是一种 F-box/LRR-重复蛋白 2激活剂,可诱导致瘤细胞凋亡,并显著抑制小鼠的肿瘤形成,还可以稳定和上调 FBXL2 水平。
体外活性: BC-1258, stabilized and increased levels of FBXL2 protein that promoted Aurora B degradation, resulting in tetraploidy, mitotic arrest and apoptosis of tumorigenic cells, and profoundly inhibiting tumor formation in athymic nude mice.?These findings uncover a new proteolytic mechanism targeting a key regulator of cell replication that may serve as a basis for chemotherapeutic intervention in neoplasia.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 4.07 mg/mL (10 mM)
关键字: LRR | F-box | BC1258 | inhibit | repeat | BC-?1258 | BC 1258 | FBXL2 | Apoptosis | tumor | Inhibitor | BC1258 | BC 1258
相关产品: 2-Deoxy-D-glucose | ZNL 02-096 | Selonsertib | WYE-354 | Evofosfamide | Nebularine | CPI-360 | Ubiquitin Isopeptidase Inhibitor I, G5 | Genistin | Farudodstat
相关库: Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Apoptosis Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途