化合物IMM-H007 T9010
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 1221412-23-2 | ¥2,320.00 | 询底价 |
25 mg | 1221412-23-2 | ¥3,980.00 | 询底价 |
500 mg | 1221412-23-2 | ¥15,200.00 | 询底价 |
1 mg | 1221412-23-2 | ¥579.00 | 询底价 |
5 mg | 1221412-23-2 | ¥1,490.00 | 询底价 |
50 mg | 1221412-23-2 | ¥5,630.00 | 询底价 |
100 mg | 1221412-23-2 | ¥7,630.00 | 询底价 |
2 mg | 1221412-23-2 | ¥866.00 | 询底价 |
1 mL | 1221412-23-2 | ¥1,690.00 | 询底价 |
Product Introduction
Bioactivity
英文名: IMM-H007
描述: IMM-H007 是一种新型降脂剂,可增加 abca1 蛋白的表达。
体外活性: IMM-H007 (H007) significantly inhibits monocyte adhesion to endothelial cells and its transendothelial migration.?Mechanistically, H007 markedly represses TNFα-induced IκBα degradation and NF-κB nuclear translocation, therefore leading to NF-κB-mediated inflammatory suppression.?Moreover, another inflammatory signaling JNK/c-Jun, which is always co-activated with NF-κB in response to pro-inflammatory stimuli, is also found to be restrained by H007 through reducing its phosphorylation status.?H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 22.5 mg/mL (60.91 mM)
关键字: JNK | Nuclear factor-κB | WS 070117 | IMM H007 | AP-1 | inflammatory | WS070117 | inhibit | AMPK | atherosclerosis | Transforming growth factor beta receptors | IMM-H007 | Activator Protein 1 | cardiac fibrosis | IMM-H 007 | JNK/c-Jun | IMMH007 | IMM-H-007 | NF-κB | Nonalcoholic fatty liver disease | NAFLD | WS-070117 | TGF-β Receptor | AMP-activated protein kinase | Nuclear factor-kappaB | Inhibitor
相关产品: XMD-17-51 | Pinusolide | Ligupurpuroside C | Pomolic acid | Doxorubicin hydrochloride | AMPK activator 12 | PF-249 | STO-609 | Platycodin D | Bempedoic acid
相关库: Nucleotide Compound Library | Bioactive Compounds Library Max | Epigenetics Compound Library | NO PAINS Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途