化合物Fedratinib hydrochloride hydrate T9251

Product Introduction
Bioactivity


英文名: Fedratinib hydrochloride hydrate

描述: Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) 是一种选择性的，ATP 竞争性和具有口服活性的JAK2抑制剂，对于JAK2和JAK2V617F 激酶的IC50均为 3 nM。它可诱导癌细胞凋亡，可研究骨髓增生性疾病。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 120 mg/mL (194.92 mM)
H2O : 97 mg/mL (157.56 mM)


关键字: STAT5 | JAK2V617F | myeloproliferative | TG-101348 hydrochloride | Janus kinase | phosphorylation | anti-proliferation | FLT3 | Apoptosis | inhibit | TG-101348 hydrochloride Hydrate | RET | orally | JAK | Fedratinib hydrochloride Hydrate | SAR 302503 hydrochloride | Fedratinib hydrochloride hydrate | anti-cancer | SAR 302503 hydrochloride Hydrate | JAK2 | Inhibitor | Fedratinib hydrochloride

相关产品: Dapivirine | Vistusertib | MK-886 | BAY1082439 | Terrestrosin D | Mevastatin | K858 (Racemic) | RHPS4 | Droxinostat | LJH685

相关库: JAK-STAT Compound Library | Drug Repurposing Compound Library | FDA-Approved Kinase Inhibitor Library | Anti-Cancer Drug Library | Inhibitor Library | Kinase Inhibitor Library | Anti-Cancer Approved Drug Library | EMA Approved Drug Library | Anti-Pancreatic Cancer Compound Library | Orally Active Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途