4-甲氧基雌二醇 T9456
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mg | 26788-23-8 | ¥3,587.00 | 询底价 |
Product Introduction
Bioactivity
英文名: 4-Methoxy 17β-Estradiol
描述: 4-Methoxy 17β-Estradiol 是雌激素代谢物之一,也是 4-羟基雌二醇的甲基化代谢物。
体外活性: 4-Methoxy-17-estradiol treatment significantly decreased cell growth and increased mitotic index. Elevation of ROS and SOD activity, with a concomitant decrease in the intracellular GSH/GSSG ratio, was also detected in 4-Methoxy-17-estradiol-treated cells. Quantitative comet assay showed increased oxidative DNA damage in the 4-Methoxy-17-estradiol-treated H1355 cells, which could be significantly reduced by the anti-oxidant N-acetylcysteine (NAC)[1].
体内活性: 4-Methoxy-17-estradiol had much weaker estrogenic activity and have similar lipid-modulating effects compared to 4-hydroxyestradiol in ovariectomized female rats[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: 4Methoxy 17βEstradiol | 4-Methoxy 17beta-Estradiol | 4-Methoxy 17b-Estradiol | 4 Methoxy 17β Estradiol | 4-Methoxy 17β-Estradiol
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途