聚氧乙烯氢化蓖麻油 T9718

Product Introduction
Bioactivity


英文名: Ethoxylated hydrogenated castor oil

描述: Ethoxylated hydrogenated castor oil 是一种聚乙二醇与天然蓖麻油的混合物，可用于水包油 (o/w) 乳浊液的乳化和增溶，是动物实验的良好助溶剂。

体内活性: Nearly 20% of Ethoxylated hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake[1]. 20% Ethoxylated hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice[2]. Ethoxylated hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females[2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 100 mg/mL


关键字: Inhibitor | PEG | Macrogolglycerol hydroxystearate | PEG-40 hydrogenated castor oil | emulsion | Ethoxylated hydrogenated castor oil | Castor oil, hydrogenated, polyethoxylated | cosolvent | inhibit

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途