十四烷基硫代乙酸 T9808
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 2921-20-2 | ¥663.00 | 询底价 |
500 mg | 2921-20-2 | ¥6,450.00 | 询底价 |
1 mL | 2921-20-2 | ¥397.00 | 询底价 |
25 mg | 2921-20-2 | ¥1,160.00 | 询底价 |
200 mg | 2921-20-2 | ¥3,970.00 | 询底价 |
5 mg | 2921-20-2 | ¥413.00 | 询底价 |
1 mg | 2921-20-2 | ¥185.00 | 询底价 |
100 mg | 2921-20-2 | ¥2,820.00 | 询底价 |
50 mg | 2921-20-2 | ¥1,830.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Tetradecylthioacetic acid
描述: Tetradecylthioacetic acid 是一种合成脂肪酸,在 β 位具有硫取代。这种修饰使 TTA 无法进行完全的 β-氧化并增加其生物活性,包括激活过氧化物酶体增殖物激活受体 (PPAR),优先选择 PPARα。
体内活性: Mice receiving HFD supplemented with 0.75% (w/w) TTA had significantly lower body weights compared to mice fed the diet without TTA. Plasma triacylglycerol (TAG) was reduced 3-fold with TTA treatment, concurrent with increase in liver TAG. Total cholesterol was unchanged in plasma and liver. However, TTA promoted a shift in the plasma lipoprotein fractions with an increase in larger HDL particles. Histological analysis of the small intestine revealed a reduced size of lipid droplets in enterocytes of TTA treated mice, accompanied by increased mRNA expression of fatty acid transporter genes. Expression of the cholesterol efflux pump Abca1 was induced in the small intestine, but not in the liver. Scd1 displayed markedly increased mRNA and protein expression in the intestine of the TTA group[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 60 mg/mL (207.98 mM)
关键字: Peroxisome proliferator-activated receptors | β-Oxidation | inhibit | fatty acid oxidation | Inhibitor | PPAR | 2-(Tetradecylthio)acetic acid | hypolipidemia | Tetradecylthioacetic acid
相关产品: Rosiglitazone maleate | Fucosterol | Bilobetin | Erycibelline | Ertiprotafib | Abietic Acid | Darglitazone | Choline Fenofibrate | Balaglitazone | Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
相关库: Drug Repurposing Compound Library | Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Human Metabolite Library | Anti-Cancer Clinical Compound Library | Nuclear Receptor Compound Library | DNA Damage & Repair Compound Library | Metabolism Compound Library | Anti-Pancreatic Cancer Compound Library
十四烷基硫代乙酸 T9808信息由TargetMol中国为您提供,如您想了解更多关于十四烷基硫代乙酸 T9808报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途