阿维鲁单抗 T9903

Product Introduction
Bioactivity


英文名: Avelumab

描述: Avelumab 是人 IgG1 抗PD-L1单克隆抗体，具有潜在的抗体依赖性细胞介导的细胞毒性作用。

动物实验: Female C57BL/6 mice are used in this study. Subcutaneous tumor injections are carried out by inoculating C57BL/6 mice with 1×105 MB49 parental cells on the right shaved flank. Tumor growth is measured with calipers and 8 days post-inoculation mice are assigned to treatment groups. Tumor-bearing mice are treated with Avelumab (400 μg per 100 μL) and injected i.p. three times, 3 days apart. Since Avelumab is a human IgG1, three injections have to be compressed within a 7 to 9 day window (i.e., days 9, 12, and 15 post-tumor inoculation) to avoid the onset of neutralizing mouse anti-human Ig[3].

存储条件: store at low temperaturestore at -20°C

关键字: Avelumab | Inhibitor | inhibit | MSB0010718C | MSB 0010718C

相关产品: PD-1/PD-L1-IN-10 | CAY10678 | Rosnilimab | PD-1-IN-17 | Spartalizumab | Atezolizumab | ARB-272572 hydrochloride | PD-1/PD-L1-IN-27 | Durvalumab | Reozalimab

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途