鸭嘴花碱酮 TC0039

Product Introduction
Bioactivity


英文名: Vasicinone

描述: Vasicinone 是一种喹唑啉类生物碱，分离自凡士林植物中。它是具有研究帕金森病和其他氧化应激相关神经退行性疾病的潜力。

体外活性: The aerial parts of Peganum harmala L. (APP) is a well-known and effective herbal medicine in China, and has been commonly used for treating various ailments, including cough and asthma. OBJECTIVES: To evaluate the antitussive, expectorant, and bronchodilating effects of the quinazoline alkaloids (±)-vasicine (VAS), deoxyvasicine (DVAS) (both isolated from the alkaloid fraction of APP) and (±)-Vasicinone (VAO) (synthesized from VAS). CONCLUSIONS:Quinazoline alkaloids VAS, VAO, and DVAS have significant antitussive, expectorant, and bronchodilating activities. VAS, VAO, and DVAS are the active ingredients in APP, which can be used to treat respiratory disease.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 12 mg/mL (59.34 mM)


关键字: Adhatoda | quinazoline | Parkinson | stress | Inhibitor | inhibit | alkaloid | Vasicinone | vasica | oxidative | plant | neurodegenerative | disorders

相关库: Anti-Tumor Natural Product Library | Anti-Cancer Compound Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Alkaloid Natural Product Library | Traditional Chinese Medicine Monomer Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Bioactive Compound Library

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