牛磺猪去氧胆酸 TJA2398

Product Introduction
Bioactivity


英文名: Taurodeoxycholic acid sodium hydrate

描述: Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate) 通过阻断钙介导的凋亡通路和 Caspase-12的活化来阻止细胞凋亡。它可用于原发性胆汁性肝硬化、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤积和肌萎缩侧索硬化症。

体内活性: At all infusion rates, taurohyodeoxycholic acid caused a greater (P < 0.001) secretion of biliary lecithin compared to the other bile salts. There were no significant differences in the biliary secretion of cholesterol and proteins. Electron microscopy showed the recruitment of vesicles and lamellar bodies around and within bile canaliculi. In conclusion, taurohyodeoxycholic promotes a biliary lecithin secretion greater than expected from physicochemical predictions, representing a novel secretory property with potential pharmacological relevance[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 125 mg/mL (231.18 mM)


关键字: Taurodeoxycholic acid sodium | Taurodeoxycholic acid sodium Hydrate | Inhibitor | Sodium taurodeoxycholate | Taurodeoxycholic acid sodium hydrate | Taurohyodeoxycholic acid sodium | Taurodeoxychloic Acid sodium Hydrate | Caspase | Apoptosis | inhibit | Sodium taurodeoxycholate Monohydrate

相关产品: Danshensu | α-Tocopherol phosphate disodium | Ursonic Acid | Ibandronate sodium monohydrate | BTR-1 | Anticancer agent 133 | Diphenyl disulfide | Anticancer agent 153 | Didymin | Nocodazole

相关库: Anti-Tumor Natural Product Library | Pyroptosis Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Natural Product Library for HTS | Apoptosis Compound Library | NO PAINS Compound Library | Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途