APRIL/TNFSF13, Human, 重组蛋白 (Flag & His) TMPJ-00137
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 μg | TMPJ-00137 | ¥1,770.00 | 询底价 |
10 μg | TMPJ-00137 | ¥820.00 | 询底价 |
500 μg | TMPJ-00137 | ¥14,600.00 | 询底价 |
1 mg | TMPJ-00137 | ¥20,700.00 | 询底价 |
Product Introduction
Bioactivity
英文名: APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
描述: APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL binds to heparan sulfate proteoglycans (HSPGs) independently of its binding to TACI and BCMA. APRIL can form bioactive heterotrimers with BAFF, and these circulate in the serum of patients with rheumatic immune disorders. APRIL enhances the proliferation and survival of plasma cells and also promotes T cell-dependent humoral responses. APRIL levels are elevated in the serum during coronary artery disease, and it is also elevated in many cancers primarily due to expression by tumor-infiltratin neutrophils.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: CD-256 | TRDL 1 | TALL2 | TALL 2 | CD 256 | TNFSF-13 | TRDL1 | TNFSF 13
APRIL/TNFSF13, Human, 重组蛋白 (Flag & His) TMPJ-00137信息由TargetMol中国为您提供,如您想了解更多关于APRIL/TNFSF13, Human, 重组蛋白 (Flag & His) TMPJ-00137报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途