TRAIL R2/DR5/TNFRSF10B, Mouse, 重组蛋白 (Avi & His), Biotinylated TMPJ-00245
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 μg | TMPJ-00245 | ¥6,130.00 | 询底价 |
20 μg | TMPJ-00245 | ¥2,260.00 | 询底价 |
Product Introduction
Bioactivity
英文名: TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
描述: Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: CD 262 | CD-262
TRAIL R2/DR5/TNFRSF10B, Mouse, 重组蛋白 (Avi & His), Biotinylated TMPJ-00245信息由TargetMol中国为您提供,如您想了解更多关于TRAIL R2/DR5/TNFRSF10B, Mouse, 重组蛋白 (Avi & His), Biotinylated TMPJ-00245报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途