TIM-3/KIM-3/HAVCR2, Human, 重组蛋白 (hFc & His) TMPJ-00599
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
500 μg | TMPJ-00599 | ¥12,100.00 | 询底价 |
50 μg | TMPJ-00599 | ¥1,650.00 | 询底价 |
10 μg | TMPJ-00599 | ¥540.00 | 询底价 |
1 mg | TMPJ-00599 | ¥17,400.00 | 询底价 |
Product Introduction
Bioactivity
英文名: TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
描述: Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
存储条件: Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month
关键字: FLJ-14428 | FLJ 14428 | TIMD 3 | TIMD-3 | KIM3 | TIM 3 | KIM 3
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途